This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.
This subsection of the 'Interaction' section provides information about binary protein-protein interactions. Alcohol 43, 571–580. Neurosci. delivery. All datasets generated for this study are included in the manuscript and/or the Supplementary Files.
Science 301, 805–809. BK is a shareholder and the CEO of Neuracle Science Co., Ltd. SPX mRNA were strongly detected in the medial habenula (mHb) and suprachiasmatic nucleus (SCN) of the hypothalmus. lentivirus, AAV, adenovirus, MMLV, MSCV, baculovirus), VectorBuilder Custom and pre-made pooled libraries (ie. Cannulae for i.c.v.
Mol. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.
This section provides information on the disease(s) and phenotype(s) associated with a protein.
This section describes post-translational modifications (PTMs) and/or processing events.
This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.
This subsection of the PTM / Processing section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).
This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.
Manual validated information which has been generated by the UniProtKB automatic annotation system.c-fos expression was also increased in the basolateral (BLA) and central amygdala (CeA).
Metab. In Pavlovian fear-conditioned mice, SG2A decreased contextual and auditory fear memory consolidation but accelerated the extinction of acquired fear memory without altering innate fear and recognition memory.
Galanin receptors – known as GAL1, GAL2 and GAL3 – are activated by the endogenous peptides galanin and galanin-like peptide and constitute the currently known galanin receptor family. doi: 10.1016/j.neulet.2016.05.026, Dohrenwend, B. P., Turner, J. SY, AR-A, B-JH, J-WS, D-HK, GS, HK, S-GK, DK, and BK designed the research. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).
U.S.A. 102, 17489–17494. Whereas GAL exerts both Gq- and β-arrestin-mediated signaling of GAL2 receptor, SPX shows a biased agonism favoring G-protein-mediated signaling (Reyes-Alcaraz et al., 2018). SWISS-MODEL Repository - a database of annotated 3D protein structure models, Database of comparative protein structure models, evolutionary genealogy of genes: Non-supervised Orthologous Groups, The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms, Identification of Orthologs from Complete Genome Data, Database for complete collections of gene phylogenies, Integrated resource of protein families, domains and functional sites, Protein Motif fingerprint database; a protein domain database, Simple Modular Architecture Research Tool; a protein domain database, PROSITE; a protein domain and family database. Other users need a Commercial license, Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. Cell. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. Neuropeptides 39, 239–243. Biol. piRNA Summary. Does kisspeptin belong to the proposed RF-amide peptide family?
Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.
This section provides any useful information about the protein, mostly biological knowledge.
Mice were allowed to recover for 2 weeks, singly housed. SY and AR-A analyzed the data.
A type of phylogenetic evidence whereby an aspect of a descendent is inferred through the characterization of an aspect of a ancestral gene.Mice were randomly assigned to two groups (Sham or CORTI). Statistical differences between individual groups were evaluated using Student’s t-tests and/or analyses of variance followed by Newman-Keuls tests as a post hoc comparison. (L) α-MSH secretion in cultured POMC neurons in response to SG2A.
Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. GALR2 (Galanin Receptor 2) is a Protein Coding gene. (2015). Anti-obesity effect of intranasal administration of galanin-like peptide (GALP) in obese mice.
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